The Connectivity Map

The Connectivity Map is a catalog of gene-expression data collected from human cells treated with chemical compounds and genetic reagents. Newly developed laboratory and computational methods to reduce the number of necessary genomic measurements have enabled the Broad Institute, in collaboration with the NIH LINCS program, to significantly increase the size of the gene expression database and along with it, our potential to connect human diseases with the genes that underlie them and the drugs that treat them.